Objective To investigate the level of self-advocacy ability of female breast cancer patients with chemotherapy，and to analyze its influencing factors，so as to provide references for clinical implementation of targeted intervention. Methods A total of 240 breast cancer patients with chemotherapy were investigated by general data questionnaire，Female Self-Advocacy in Cancer Survivorship Scale，Social Support Rating Scale，and Sense of Coherence Scale. Results The self-advocacy score of 240 breast cancer chemotherapy patients was（68.89±10.66）；there was a positive correlation between self-advocacy and social support（r=0.723，P<0.001）；it was also positively correlated with the sense of coherence（r=0.569，P<0.001）. The results of multiple linear regression analysis showed that age，educational level，social support and the sense of coherence were the influential factors of self-advocacy ability of breast cancer patients with chemotherapy，which explained 61.4% of the total variation. Conclusion The self-advocacy ability of breast cancer patients with chemotherapy is at medium level，and there are some problems in self-decision-making，effective communication with medical staff and seeking social support. Medical staff should pay attention to patients with advanced age and low education level，and help patients improve their sense of coherence and their ability to obtain and use social support，so as to improve the level of self-advocacy of patients.

Objective To investigate the application effect of a graded management program of hand-foot syndrome（HFS） in patients with breast cancer who received chemotherapy. Methods Convenience sampling method was adopted to select breast cancer patients who received chemotherapy in the breast surgery department of a tertiary A hospital in Wuhan. According to the time of admission，55 patients admitted from April 2022 to September 2022 were included in the experimental group，in which the graded management program was carried out according to the occurrence of HFS. 55 patients admitted from October 2021 to March 2022 were included in the control group，in which the routine chemotherapy care was carried out. Interventions in both groups lasted until 3 days after the last chemotherapy. The incidence of HFS and its impact on quality of life 3 days after the final chemotherapy were compared between the 2 groups. Results The incidence of HFS was 34.55% in the experimental group and 58.18% in the control group，and there were significant differences in the incidence and grade of HFS between the 2 groups（P<0.05）. The total score of life quality scale in the experimental group was 15.00（13.00，17.00） and 19.00（17.00，22.00） in the control group. The life quality of patients in the experimental group was significantly higher than that in the control group（P<0.001）. Conclusion The graded management program for breast cancer patients with HFS can reduce the incidence and grade of HFS，and can help to improve the quality of life in breast cancer patients who received chemotherapy.

Objective To explore the constituent elements of nurses’ humanistic literacy,to construct the self-rating scale of nurses’ humanistic literacy and verify its reliability and validity. Methods From July to December 2020,on the basis of reviewing the latest literature,the initial item pool of the scale was formed through 2 rounds of expert consultation and pre-investigation. This scale was tested among 1 000 nurses in hospitals across the country. SPSS was used to analyze the reliability,and AMOS was used for confirmatory factor analysis. Results The self-rating scale of nurses’ humanistic literacy consisted of 6 dimensions and 54 items. The Cronbach’s α coefficient of the total scale was 0.982;the split-half reliability of the total scale was 0.962;the retest reliability of the total scale was 0.758. 6 common factors were extracted by exploratory factor analysis,which explained 68.089% of the total variance. The one-dimension/multi-factor model’s /df was 2.495;NFI was 0.800;modified standardized moderation index was 0.876;CFI was 0.922;TLI was 0.915,and RMSEA was 0.055. Conclusion This study determined the constituent elements of humanistic literacy of nurses in China. The scale with good reliability and validity can further provide support for the investigation of the humanistic literacy level of nurses in China. It can also provide a basis and reference for nursing management to develop interventions.

Objective To investigate the effects of intervention strategies based on self-efficacy theory on nutritional status and cancer-induced fatigue（CRF） after total thoracoscopic esophageal cancer. Methods A total of 119 patients with esophageal cancer admitted to the Second Affiliated Hospital of Nanchang University from January 2017 to December 2020 were selected by convenience sampling method. They were divided into an experimental group（n=59） and a control group（n=60） according to random number method. Patients in the control group received conventional nursing,while patients in the experiment group take the self-efficacy theory as the instruction intervention strategy. The self-efficacy,nutritional status and T₄ CRF of 2 groups of patients were compared in the hospital（T₀）,1 month after discharge（T₁）,3 months after discharge（T₂）,6 months after discharge （T₃）,and 1 year after discharge（T₄）. Results The self-efficacy score of the experimental group was higher than that of the control group at different time points after intervention,and the risk score of nutritional status was lower than that of the control group,with statistical significances（P<0.05）. At T₄,the CRF score of the experiment group （33.90±6.30） was significantly lower than that of control group（44.93±7.66）（P<0.001）. Conclusion Nursing intervention strategies based on self-efficacy theory can significantly increase the self-efficacy of patients after thoracoscopic esophageal cancer surgery,improve their nutritional status,and alleviate CRF.